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Eur J Med Chem (2017) 141:11337

According to researchers, significant increase in skin thickness was observed, which may indicate potential dermal modifications related to hormonal changes

Natural compounds derived from plants (such as sulforaphane, corosolic acid, taxifolin, reserpine, quercetin, Z-ligustilide and curcumin) and marine constituents (fucoxanthin) have been shown to activate Nrf2 signaling through epigenetic regulation (Su et al., 2013